From a graphical standpoint, all of the characters and locations seem to portray their silver-screen counterparts pretty closely. The lines could have been a little smoother and of course don't look as clean as the 360 version, but given the system's capabilities, it isn't all that bad looking.
Audio-wise, Meet the Robinsons is everything you would expect from a film inspired game. The vocals are either done by the original actors, or close enough impersonators that you can't really tell, and the musical score of the game fits nicely with the soundtrack of the film. From a more technical aspect, I never found the characters' comments to be too frequent or repetitive and they rarely got annoying. The only exception might be the game's help system in the Robinson family robot, Carl.